Additionally, discontinuation of a concomitantly utilised cytochrome P450 3A4 inducer might result in an increase in hydrocodone plasma concentrations. Monitor patients receiving hydrocodone/acetaminophen and any cytochrome P450 3A4 inhibitor or inducer for indications of respiratory depression or sedation. Mechanism of Motion: Acetaminophen-hydrocodone blend generated analgesia by tw... http://thomasf271gjm1.izrablog.com/profile