2. Histamine Receptor Antagonism: Some sedatives, for instance antihistamines, exert their sedative effects by blocking histamine receptors in the Mind, especially H1 receptors. Histamine performs a task in wakefulness and arousal, so blocking its effects promotes sedation and sleepiness. Don’t mix sedatives with each other or with other remedies https://milomhxma.bloggazza.com/32134643/side-effects-of-sedative-drugs-risks-warnings-solutions