2. Histamine Receptor Antagonism: Some sedatives, for example antihistamines, exert their sedative effects by blocking histamine receptors inside the brain, specially H1 receptors. Histamine performs a role in wakefulness and arousal, so blocking its effects promotes sedation and sleepiness. Don’t combine sedatives with each other or with other remedies https://sedativesdrugs10763.anchor-blog.com/13361658/sedatives-drugs-list-common-medications-and-their-applications